RESUMO
The importance of religiousness in idiopathic Parkinson's disease (IPD) has been the subject of conflicting research. The impact of religiousness on quality of life and depressive symptoms has also been poorly studied in this population. This study investigated the correlation between religiousness and quality of life in patients with IPD. We evaluated 37 patients with IPD (according to the criteria of the Movement Disorders Society) who were from an outpatient clinic specializing in movement disorders in Brazil. We assessed the patients using the Duke University Religion Index and scales for motor impairment, cognition, quality of life, and depression. Spearman's test was used to check for possible correlations between the different dimensions of religiousness and the clinical variables analyzed. Patients with a worse quality of life and more depressive symptoms showed greater intrinsic religiousness.
RESUMO
Objetivos: Avaliar em mulheres com doença de Parkinson e disfunções urinárias as correlações dos sintomas urinários com os sintomas motores e disfunções mentais. Verificar a prevalência de hiper-reflexia detrusora (HD), bem como analisar em longo prazo a gravidade do desempenho motor, estadiamento de Hoenh-Yahr, habilidades funcionais, funções neuropsicológicas e a magnitude da progressão desses aspectos clínicos e do declínio cognitivo em pacientes com HD. Sujeitos e Métodos: Estudamos uma coorte ambulatorial de sessenta e três (63) pacientes com DP cujos aspectos neurológicos foram avaliados com a utilização das escalas Unified Parkinson's Disease Rating Scale (UPDRS) e a escala de Hoehn-Yahr. As habilidades funcionais foram avaliadas pela escala Schwab & England e a função urológica foi quantificada pela International Prostatic Symptom Scale (IPSS) e qualificada pelo estudo urodinâmico. Foram então categorizados dois grupos: pacientes com e sem HD. Após sete anos os mesmos parâmetros foram reavaliados e a escala Montreal Cognitive Assessment (MoCA)-versão brasileira foi utilizada para o rastreamento neuropsicológico. Resultados: Na avaliação inicial foi constatada correlação positiva entre os sintomas urinários e a gravidade da doença, porém não havia correlação entre a sintomatologia urinária e os sintomas mentais. Sintomas motores, estágio de gravidade da doença e habilidades funcionais eram mais graves em pacientes com HD. Na reavaliação, os grupos não apresentavam diferença quanto à magnitude da progressão dos sintomas motores, do estadiamento da doença e das inabilidades funcionais. Foi observado no grupo com HD maior declínio cognitivo e uma nítida progressão dos escores mentais com risco aumentado para demência...
Objectives: This long-term study in women with Parkinson's disease (PD) and lower urinary tract dysfunctions aimed to verify the correlation of urinary symptoms with the severity of the disease and mental functions. Verify the prevalence of detrusor hiper-reflexia (DH) and analyze the severity of motor symptoms, Hoehn and Yahr stage, functional abilities and neuropsychological functions, as well as analyze the progression of these clinical aspects and cognitive decline in patients with DH. Subjects and Methods: We studied a cohort of sixty-three (63) PD patients whose neurological aspects were evaluated with the Unified Parkinson's Disease Rating Scale (UPDRS) and Hoehn-Yahr scale. Functional abilities were evaluated by Schwab and England scale and the urological function was quantified by International Prostatic Symptom Scale (IPSS) and qualified by urodynamic study. Two groups were then categorized: patients with and without HD. After seven years the same parameters were re-evaluated and the cognitive functions were assessed with the Montreal Cognitive Assessment (MoCA). Results: At baseline a correlation between urinary symptoms and motor dysfunction was verified but no correlation between urinary symptoms and mental symptoms was observed. The severity of motor symptoms, stage of the disease and functional disabilities were significant in patients with DH. In the follow up, the groups were similar in regards to progression of motor symptoms, Hoehn and Yahr stage and functional disabilities. On the other hand, decline in cognitive function and clear progression of mental scores and risk for dementia was observed in the group with DH. Conclusion: Urinary symptoms are correlated with the severity of the Parkinson's disease...
